Trintellix Patient Assistance Program

Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: October 7, 2025

Struggling with the high cost of your Trintellix prescription? At The Rx Advocates, we help make your medication more affordable. We connect you with patient assistance programs that provide greater savings than coupons or discount cards. Through manufacturer Patient Assistance Programs, eligible patients may pay a low, fixed monthly fee. The Rx Advocates handle the entire process so you can stay on treatment without financial stress.

What is the Trintellix Patient Assistance Program?

The Trintellix Patient Assistance Program provides aid for patients who need help affording their medication. This program is offered by the manufacturer to help qualifying individuals access their prescription at reduced or no cost. While coupons may provide short-term savings, PAPs offer more comprehensive and long-term solutions for people requiring ongoing depression treatment. The Rx Advocates connect patients with these manufacturer programs, assist with applications, and help maintain enrollment in the Trintellix PAP.

How to Qualify

Qualification for patient assistance programs depends on household income levels and residency status. We assess each application individually to determine eligibility.

Typical requirements to qualify include:

  • Individuals qualify if they earn up to $40,000 annually
  • Couples qualify if they earn up to $60,000 annually
  • Larger families qualify if they earn up to $100,000 annually
  • U.S. residency and a valid prescription

Guidelines differ from one patient assistance program to another. Contact us so we can review your specific circumstances and determine if you qualify.

Pricing

Cost of Trintellix
with The Rx Advocates

The monthly service fee depends on the number of medications you take. For example:

1 Medication

$80 / Month

2 Medications

$90 / Month

3 Medications

$100 / Month

4 Medications

$110 / Month

NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.

The Rx Advocates Can Help Reduce Trintellix Costs

The Rx Advocates provide aid for people seeking medication through patient assistance programs. We partner with more than 100 United States-based pharmaceutical manufacturers’ patient assistance programs. The medications we help provide include the top 100 prescribed in the United States, with access to over 800 brand-name FDA-approved medications.

We are not an insurance plan, prescription discount card, or Trintellix coupon. Our team connects patients with manufacturer assistance programs by handling all paperwork, coordinating with healthcare providers, and submitting applications. We follow up to ensure approvals are processed and monthly refills arrive without interruption.

Cost of Trintellix vs Other Options

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Trintellix Cost
(using The Rx Advocates)
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30-Day Supply
$80.00/month
Goodrx logo
Trintellix Price
(estimated retail*)
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One Dose Pack
$622.74

* Source: GoodRx.com

Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.

Why PAPs Are Better Than Coupons

Before relying on a Trintellix coupon, understanding its potential disadvantages is important. Patient assistance programs provide more comprehensive and stable solutions than coupons can offer.

Disadvantages of coupons

  • Restrictions: Coupons may have limits on redemption frequency or discount amounts
  • Copay Accumulators: May not count toward your insurance out-of-pocket maximum, providing less overall savings
  • Expiration Dates: Limited validity means coupons become useless after expiration
  • Limited Coverage: Provide only short-term savings rather than long-term solutions

Advantages of PAP through The Rx Advocates

  • Fixed Monthly Cost: Pricing remains stable regardless of retail price changes
  • No Expiration: Continued access maintained throughout your qualification
  • Direct From Manufacturer: Medication supplied reliably from the source each month
  • Broad Support: Access to over 800 FDA-approved medications

Frequently Asked Questions (FAQ)

Here are answers to common questions about Trintellix and patient assistance programs below.

With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.

  • 1 Medication (Trintellix only) – $80 per month
  • 2 Medications (Trintellix + 1 other) – $90 per month
  • 3 Medications (Trintellix + 2 others) – $100 per month
  • 4+ Medications – $110 per month

Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.

As of now, Trintellix typically costs around $622.74 for a 30-day supply at retail pharmacies.

The price can differ based on several factors:

  • Dosage: Available in 5 mg, 10 mg, and 20 mg tablet strengths
  • Location: Patient’s geographic area affects pricing
  • Pharmacy: Each pharmacy’s location influences costs
  • Insurance Coverage: Health insurance presence significantly reduces out-of-pocket expenses

Most programs follow these income requirements: individuals earning up to $40,000 annually, couples earning up to $60,000 annually, and large families earning up to $100,000 annually may qualify. Contact us so we can review your specific living situation to determine if you qualify.

The Rx Advocates handle enrollment and refill processes by assembling required documentation with your prescriber, submitting applications to manufacturers, and coordinating medication deliveries to prevent treatment gaps.

About Trintellix

Trintellix (vortioxetine) is an antidepressant medication. It is primarily prescribed for adults to treat Major Depressive Disorder (MDD).

Mechanism of action: Trintellix works by enhancing serotonin activity in the brain. It prevents serotonin from being recycled by brain cells and acts directly on serotonin receptors.

Additional uses: Trintellix is specifically approved for treating Major Depressive Disorder in adults. Take Trintellix exactly as prescribed at the same time every day.

Form & administration: Administered by the patient as an oral tablet taken once daily. Available in 5 mg, 10 mg, and 20 mg strengths. Can be taken with or without food.

Side effects:

  • Common: nausea, constipation, vomiting.
  • Serious: serotonin syndrome, abnormal bleeding, manic episodes.
  • Warning: not for patients allergic to vortioxetine; cannot be taken with MAOIs or within 14 days of stopping MAOI therapy; provide complete medical history to healthcare provider.

Get Started Today

At The Rx Advocates, our goal is to assist people in obtaining their prescription medication at affordable prices each month. If Trintellix costs are making treatment difficult, we can connect you with patient assistance programs and provide ongoing support.

Contact us today to review your specific situation and determine if you qualify for patient assistance programs.

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