Is your Xifaxan medication too expensive? Many people struggle affording their Xifaxan prescription, even with coupons. Monthly medications like Xifaxan can be financial burdens for many patients, and coupons may not always provide enough savings.
The Rx Advocates connect you to manufacturer Patient Assistance Programs (PAPs) that deliver substantial savings on Xifaxan and other medications. Through PAPs, eligible patients pay a low, fixed monthly fee. We handle the entire process so you can stay on treatment without letting high medication costs hold you back from your health goals.
What is the Xifaxan Patient Assistance Program?
Pharmaceutical manufacturers operate PAPs to help eligible patients access medications they otherwise couldn’t afford. Xifaxan’s program ensures ongoing medication access without depending on temporary coupons.
The Rx Advocates offer affordable access to manufacturer assistance programs for more than 800 FDA-approved medications, including the top 100 prescribed by doctors in the United States. We partner with over 100 pharmaceutical manufacturers to help patients save on monthly prescriptions. Our services come with no hidden fees or additional costs. We handle application processes, coordinate with healthcare providers, and manage manufacturer submissions.
How to Qualify
Most patient assistance programs require people to meet certain criteria to qualify. We review individual information to determine if you qualify for our assistance.
Typical requirements to qualify include:
- Individuals qualify if they earn up to $40,000 annually
- Couples qualify if they earn up to $60,000 annually
- Larger families qualify if they earn up to $100,000 annually
- U.S. residency and a valid prescription
Guidelines may differ from one patient assistance program to another. Contact us so we can review your individual information.
Cost of Xifaxan
with The Rx Advocates
The monthly service fee depends on the number of medications you take. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.
The Rx Advocates Can Help Reduce Xifaxan Costs
Our mission is providing assistance to people with obtaining prescription medications at affordable prices. We understand how expensive medications can be and paying cash for them is not possible in some cases.
We’re not a coupon provider, insurance plan, or discount card. Patients are charged set fees based on the number of medications they need assistance with. We handle enrollment, track applications, and coordinate deliveries so patients can access medications they need to stay healthy without worrying about cost.
Cost of Xifaxan vs Other Options
$80.00/month
$2692.54
* Source: GoodRx.com
Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.
Why PAPs Are Better Than Coupons
While a Xifaxan coupon can provide some savings, it may also have limitations that could ultimately limit potential for significant savings. Patient assistance programs provide more substantial savings and are often available year-round.
Disadvantages of coupons
- Restrictions: May only be available for limited time or apply to specific number of refills
- Copay Accumulators: May not be available to all patients or only provide modest discounts, leaving significant out-of-pocket costs
- Expiration Dates: Time-limited validity creates savings gaps
- Limited Coverage: Even with coupons, patients face substantial financial burdens
Advantages of PAP through The Rx Advocates
- Fixed Monthly Cost: Set service fees based on medication count
- No Expiration: Year-round availability without time restrictions
- Direct From Manufacturer: Medication supplied reliably from the pharmaceutical source
- Broad Support: Help patients access medications at little or no cost, regardless of income or insurance status
Frequently Asked Questions (FAQ)
Here is some key information about Xifaxan costs and patient assistance programs.
With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.
- 1 Medication (Xifaxan only) – $80 per month
- 2 Medications (Xifaxan + 1 other) – $90 per month
- 3 Medications (Xifaxan + 2 others) – $100 per month
- 4+ Medications – $110 per month
Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.
Costs are extraordinary without patient assistance, and epends on several factors:
- Dosage: Prescribed dosage amount from doctor (available in 200 mg and 550 mg tablets)
- Location: Patient’s geographic area impacts pricing
- Pharmacy: Pharmacy location influences costs
- Insurance Coverage: Whether patient has health insurance significantly affects expenses
Annual income for individual households must not exceed $40,000, couples must not go over $60,000, and large family households must not exceed $100,000. Reach out so we can determine if you meet guidelines.
We help patients access medications like Xifaxan at little or no cost, regardless of income or insurance status. We handle application processes and coordinate with manufacturers to ensure continuous medication access.
About Xifaxan
Xifaxan (rifaximin) is an antibiotic medication. It is primarily prescribed to treat traveler’s diarrhea (TD), hepatic encephalopathy in adults, and irritable bowel syndrome with diarrhea (IBS-D).
Mechanism of action: Xifaxan works by stopping bacterial growth in the intestines. Unlike many antibiotics, it stays primarily in the gut and is minimally absorbed into the bloodstream.
Additional uses: For TD, dose is 200 mg three times daily for three days at symptom onset. For hepatic encephalopathy, Xifaxan is dosed at 550 mg twice daily for as long as prescribed. For IBS-D, Xifaxan is given 550 mg three times daily for 14 days and can be used for up to two more courses in a six-month period.
Form & administration: Administered by the patient as oral tablets. Available in 200 mg and 550 mg strengths. Take with or without food.
Side effects:
- Common: nausea, dizziness, fatigue, fluid retention.
- Serious: severe allergic reactions, Clostridium difficile-associated diarrhea, liver problems.
- Warning: not for everyone; do not take if you have hypersensitivity to rifaximin or any other ingredients in Xifaxan.
Get Started Today
Don’t let high Xifaxan costs prevent you from getting the treatment you need. Patient assistance programs exist specifically to help people afford medications – many just don’t know about them.
We connect patients to these programs every day, helping them save hundreds or thousands monthly. Want to see if you qualify? Contact us now and we’ll review your situation immediately.
