Chronic pain led you to opioid medication that finally provided relief. Then opioid-induced constipation became its own problem, one that over-the-counter laxatives couldn’t touch. Your doctor prescribed Relistor because it specifically targets constipation caused by opioids without interfering with pain control. When you went to pick it up, the pharmacy staff quoted a price that seemed impossible for a medication you’d need regularly.
The Rx Advocates enrolls patients in Patient Assistance Programs (PAPs) that provide Relistor at income-based rates instead of retail pricing.
What is the Relistor Patient Assistance Program?
Pharmaceutical companies maintain programs for patients managing opioid-induced constipation who meet financial eligibility requirements. These programs supply Relistor at substantially reduced costs to qualifying applicants, ensuring treatment access regardless of ability to pay retail prices.
You provide prescription documentation and income verification. Our team completes your application, coordinates with your prescribing physician, submits materials to the manufacturer, and monitors approval. Once enrolled, Relistor ships to your home each month.
We operate as a prescription advocacy organization that facilitates access to manufacturer programs providing medications at income-determined costs rather than pharmacy retail rates.
How to Qualify
Eligibility hinges on household income and valid prescription:
- Singles earning less than $40,000 yearly
- Couples whose combined annual income is less than $60,000
- Larger families with annual income of less than $100,000
- Valid prescription from licensed healthcare provider
Even if you meet these requirements, approval isn’t guaranteed. The eligibility criteria for patient assistance vary across programs. Don’t hesitate to reach out to us to find out if you qualify.
Cost of Relistor
with The Rx Advocates
The monthly service fee depends on the number of medications you take. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.
The Rx Advocates Can Help Reduce Relistor Costs
You’ll pay a set monthly fee determined by how many medications need assistance. That fee remains constant even when retail prices increase.
Chronic pain management often requires multiple medications. Our service assists patients in various circumstances: inadequate insurance coverage, prohibitively high deductibles, or complete lack of insurance.
We don’t issue coupons or operate discount card systems. We manage applications for pharmaceutical manufacturer programs that deliver ongoing medication access at costs far below retail.
Cost of Relistor vs Other Options
$80.00/month
$3035
* Source: GoodRx.com
Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.
Why Patient Assistance Programs Beat Coupons
Coupons provide short-term relief. Patient assistance programs offer sustainable solutions.
Coupon limitations
- Pharmacy restrictions: Only accepted at certain locations
- Copay accumulators: May not apply toward your deductible
- Expiration dates: Limited validity period
- Coverage gaps: Often insufficient when medication costs are high
- Redemption requirements: Physical presentation at pharmacy needed
PAP advantages
- Substantial savings: Far exceed typical coupon discounts
- Reliable access: Consistent availability without expiration concerns
- Predictable costs: Your fee stays the same regardless of price changes
- Convenient delivery: Medication ships directly to you
Frequently Asked Questions (FAQ)
We’ve compiled answers to some of the most common questions about Relistor and patient assistance programs.
With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.
- 1 Medication (Relistor only) – $80 per month
- 2 Medications (Relistor + 1 other) – $90 per month
- 3 Medications (Relistor + 2 others) – $100 per month
- 4+ Medications – $110 per month
Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.
Without a patient assistance program, Relistor is expensive. Retail pricing varies considerably based on factors patients cannot influence.
Several factors influence the final price a patient may pay:
- Dosage: Higher prescribed strengths or quantities cost more
- Location: Prices vary by region due to healthcare and pharmacy pricing differences
- Pharmacy: Each pharmacy sets its own retail structure, which can cause major variations
- Insurance Coverage: Patients with commercial insurance may pay less, while those without coverage often face the full retail cost
This means that two patients could pay very different amounts for the same prescription, depending on where they live, where they buy their medication, and their insurance status.
Most patients meet the requirements when annual household income stays below $40k for individuals, $60k for couples, or $100k for larger families. Since manufacturer requirements can differ, The Rx Advocates assess each case individually to determine eligibility.
The Rx Advocates manage enrollment and monthly refills, coordinating all necessary paperwork with your prescribing physician, submitting completed applications to manufacturers, and arranging medication deliveries to prevent treatment interruptions.
About Relistor
Relistor is a prescription medication used to treat opioid-induced constipation in adults with chronic pain or advanced illness.
How it works: Relistor contains methylnaltrexone, which blocks opioid effects in the gastrointestinal tract without affecting pain relief in the central nervous system. This allows normal bowel function to resume while maintaining pain control.
Administration: Available as oral tablets or subcutaneous injection. Tablets are typically used for chronic non-cancer pain, while injections are prescribed for patients with advanced illness requiring palliative care. Bowel movements usually occur within 30 minutes to several hours after dosing.
Side effects:
- Common: Abdominal pain, nausea, diarrhea, flatulence, dizziness
- Serious: Severe abdominal pain, gastrointestinal perforation, opioid withdrawal symptoms
Important warnings: Relistor can cause gastrointestinal perforation, particularly in patients with conditions affecting the intestinal wall. Contact your doctor immediately if you experience severe, persistent, or worsening abdominal pain. Discontinue use if opioid pain medication is stopped. Inform your doctor about all medical conditions, especially any history of intestinal problems.
Get Started Today
Opioid-induced constipation significantly impacts quality of life and can lead to serious complications if left untreated. Some patients reduce or stop necessary pain medication to avoid constipation, sacrificing pain control. Others endure severe discomfort that affects nutrition, mobility, and daily functioning.
We created this service because managing chronic pain is difficult enough without adding financial barriers to necessary treatments. Manufacturer assistance programs have funding allocated specifically for medications like Relistor.
Contact us today to learn how patient assistance programs can help you afford Relistor treatment.
