H. pylori infection has disrupted your digestion and caused ulcers with constant stomach pain. Your gastroenterologist prescribed Pylera, explaining that this combination antibiotic therapy could eliminate the bacteria causing your symptoms. You felt relieved until the pharmacy quoted the price for a single treatment course. The cost made you consider whether you could delay treatment or simply deal with the discomfort a little longer.
At The Rx Advocates, we’ve guided many patients through this situation. We specialize in connecting people to patient assistance programs that make medications like Pylera more affordable.
What is the Pylera Patient Assistance Program?
Pharmaceutical companies sponsor programs for patients managing H. pylori infection who face financial barriers. The program ensures qualifying individuals maintain consistent access to Pylera without cost preventing proper treatment.
You provide your gastroenterologist’s prescription and household income documentation. Our team coordinates with your doctor’s office, compiles materials, submits your application, and monitors progress until approval. Once you’re enrolled, your medication ships on schedule.
We’re a drug advocacy program that helps people across the US access their medications at more affordable rates. We partner with pharmaceutical companies that offer financial assistance programs to eligible patients.
How to Qualify
Eligibility is based on several criteria. People qualify if they meet one of the following:
- Singles earning less than $40,000 yearly
- Couples whose combined annual income is less than $60,000
- Larger families with annual income of less than $100,000
- Valid prescription from licensed healthcare provider
Even if you meet these requirements, approval isn’t guaranteed. The eligibility criteria for patient assistance vary across programs. Don’t hesitate to reach out to us to find out if you qualify.
Cost of Pylera
with The Rx Advocates
The monthly service fee depends on the number of medications you take. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.
The Rx Advocates Can Help Reduce Pylera Costs
Working with us includes no hidden fees or additional application costs. What you see is what you get. We charge a fixed service fee depending on how many medications you apply for.
Our team understands the strain prescriptions place on your finances. Patients receiving prescription reimbursement, commercially insured patients, and people without any health insurance can all receive help if they qualify.
We don’t offer prescription reimbursement, coupons, savings cards, or discounts. We connect patients to assistance programs that provide a dependable, affordable way to receive your medications.
Cost of Pylera vs Other Options
$80.00/month
$376.3
* Source: GoodRx.com
Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.
Why Patient Assistance Programs Beat Coupons
While coupons can offer temporary savings, they aren’t dependable or long-term solutions. Patient assistance programs deliver greater long-term savings.
Coupon limitations
- Pharmacy restrictions: Not valid in all pharmacies
- Copay accumulators: Might not count toward out-of-pocket maximum
- Expiration dates: Usually valid only for short time
- Limited coverage: Provide only minimal assistance when retail price is high
- In-person redemption: Must present coupon to pharmacist in person
PAP advantages
- Greater savings: Deliver more substantial long-term savings
- Stable solution: More reliable than temporary coupons
- Fixed costs: Service fee remains constant regardless of retail price
- Home delivery: Medications delivered to your door at no extra cost
Frequently Asked Questions (FAQ)
We’ve compiled answers to some of the most common questions about Pylera and patient assistance programs.
With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.
- 1 Medication (Pylera only) – $80 per month
- 2 Medications (Pylera + 1 other) – $90 per month
- 3 Medications (Pylera + 2 others) – $100 per month
- 4+ Medications – $110 per month
Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.
Without a patient assistance program, Pylera is expensive. Right now, retail prices of Pylera can differ based on various factors.
Several factors influence the final price a patient may pay:
- Dosage: Higher prescribed strengths or quantities cost more
- Location: Prices vary by region due to healthcare and pharmacy pricing differences
- Pharmacy: Each pharmacy sets its own retail structure, which can cause major variations
- Insurance Coverage: Patients with commercial insurance may pay less, while those without coverage often face the full retail cost
This means that two patients could pay very different amounts for the same prescription, depending on where they live, where they buy their medication, and their insurance status.
Most patients meet the requirements when annual household income stays below $40k for individuals, $60k for couples, or $100k for larger families. Since manufacturer requirements can differ, The Rx Advocates assess each case individually to determine eligibility.
The Rx Advocates manage enrollment and monthly refills, coordinating all necessary paperwork with your prescribing physician, submitting completed applications to manufacturers, and arranging medication deliveries to prevent treatment interruptions.
About Pylera
Pylera is a combination antibiotic therapy used to treat Helicobacter pylori infection.
How it works: Pylera contains three antibiotics that work together to eliminate H. pylori bacteria from the stomach lining. The combination targets the bacteria through multiple mechanisms, which increases effectiveness and reduces the chance of antibiotic resistance developing during treatment.
Administration: Taken as part of a 10-day treatment regimen. Patients typically take three capsules four times daily along with another medication called omeprazole. The complete course must be finished even if symptoms improve earlier to ensure the infection is fully eliminated.
Side effects:
- Common: Nausea, diarrhea, abdominal pain, darkened stool, darkened tongue
- Serious: Severe allergic reactions, persistent diarrhea, numbness or tingling in hands or feet, seizures
Important warnings: Pylera contains bismuth, which temporarily darkens your tongue and stool. This is normal and resolves after treatment. Avoid alcohol during treatment and for several days after because it can cause severe reactions. Your healthcare provider should monitor for signs of nerve damage during extended treatment courses.
Get Started Today
H. pylori infection requires proper antibiotic treatment to prevent complications like ulcers and stomach cancer. Delaying treatment because of cost concerns can lead to more serious health problems that become harder and more expensive to treat later.
We believe that access to necessary medications should not depend on your financial situation. We started this business to ensure every individual can access vital medications without creating financial hardship.
Contact us today to learn more about how patient assistance programs can help you afford Pylera treatment.
