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Xifaxan Coupon & Patient Assistance Programs

Authored by Nicole Colwell, / Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: June 12, 2021

Is your Xifaxan medication too expensive? Many people struggle to afford their Xifaxan prescription, even with a Xifaxan coupon. Monthly medications like Xifaxan can be a financial burden for many patients, and coupons may not always provide enough savings. That’s why The Rx Advocates offers an alternative solution: patient assistance programs. Our services can provide even more savings on Xifaxan and other medications, making them more affordable for patients in need. Don’t let the high cost of medications hold you back from your health goals. Contact The Rx Advocates today to learn more about our patient assistance programs.

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Xifaxan Cost

(using The Rx Advocates)

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30-Day Supply

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Xifaxan Price

(estimated retail*)

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One Dose Pack

* Source:


Accessing Xifaxan patient assistance programs

The Rx Advocates offer affordable access to patient assistance programs for more than 800 FDA-approved medications, including the top 100 prescribed by doctors in the United States, such as Xifaxan. We partner with over 100 pharmaceutical manufacturers’ patient assistance programs to help patients save on their monthly prescriptions. Our services come with no hidden fees or additional costs, and patients are charged a set fee based on the number of medications they need assistance with. With The Rx Advocates, patients can access the medications they need to stay healthy, without worrying about the cost.

  • 1 Medication (Xifaxan only) – A set fee of $80 each month
  • 2 Medications (Xifaxan + 1 other) – A set fee of $90 each month
  • 3 Medications (Xifaxan + 2 others) – A set fee of $100 each month

The limitations of a Xifaxan Coupon

While a Xifaxan coupon can provide some savings, it may also have limitations that could ultimately limit the potential for significant savings. For example, Xifaxan coupons may only be available for a limited time, or they may only apply to a specific number of refills. Additionally, coupons may not be available to all patients or may only provide a modest discount, leaving patients with a significant out-of-pocket cost. By contrast, patient assistance programs like those offered by The Rx Advocates can provide more substantial savings and are often available year-round. These programs can also help patients access medications like Xifaxan at little or no cost, regardless of their income or insurance status.

How much does Xifaxan cost?

As of January 2024, the average retail cost of Xifaxan is $2,693.00.

The cost of Xifaxan is dependent on the following factors:

  • The dosage amount prescribed by the doctor.
  • The location of the patient.
  • The location of the pharmacy.
  • Whether or not the patient has health insurance.

How much will it cost with The Rx Advocates?


How much will it cost with The Rx Advocates?

If approved, by the Xifaxan Patient Assistance Program, you’ll be charged a fixed monthly service fee. This fee varies depending on the number of medications you qualify for. For example:

1 Medication

$80 / Month

2 Medications

$90 / Month

3 Medications

$100 / Month

4 Medications

$110 / Month

1 Medication

$80 / Month

2 Medications

$90 / Month

3 Medications

$100 / Month

4 Medications

$110 / Month

NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35. Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.

How to qualify for patient assistance?

Most patient assistance programs require people to meet the following criteria to qualify for their program:
  • The annual income for individual households must not exceed $40,000.
  • The annual income for couples must not go over $60,000.
  • The annual income for large family households must not exceed $100,000.
The guidelines may differ from one patient assistance program to another. Please contact us so we can review your individual information and determine if you qualify for our assistance.

Xifaxan coupon & patient assistance FAQ's

Xifaxan (rifaximin) is a prescription medication that can treat a variety of conditions including traveler’s diarrhea (TD), hepatic encephalopathy in adults, and irritable bowel syndrome with diarrhea (IBS-D).

Xifaxan is available in the tablet sizes 200 mg and 550 mg.

For TD, the dose is 200 mg three times daily for three times at the onset of symptoms.

For hepatic encephalopathy, Xifaxan is dosed at 550 mg twice daily for as long as prescribed by the doctor.

For IBS-D, Xifaxan is given 550 mg three times daily for 14 days and can be used for up to two more courses in a six month period.

This medication is not for everyone. Do not take this medication if you have hypersensitivity to rifaximin or any other ingredients in Xifaxan.

There are a couple of alternatives to Xifaxan: 

The Rx Advocates does not offer coupons but we still feel it is important that people understand how coupons work. They do not offer the type of savings that can really make a difference from month to month. When people are prescribed Xifaxan, they will go online and search for coupons and understandably so because it is expensive to pay for out of pocket.

Xifaxan coupons still leave people paying hundreds of dollars out of pocket.

There are other names for prescription drug coupons such as copay cards, copay coupons, copay assistance programs, and pharmacy coupons. These cards represent a program that has been funded by a pharmaceutical company to help reduce the out-of-pocket costs for patients. This sounds great; however, there are limitations such as the following:

  • Coupons usually last for only a limited time. They do not provide savings from month to month.
  • Some coupons help the patient with the initial filling of a prescription but the subsequent fillings are not covered.
  • Patients will have to leave their homes to go to the pharmacy to pick up their medication(s) and present their coupons to the pharmacist. 

Prescription discount cards are cards that give people access to lower drug costs for their prescription medications. They are most beneficial for people who have to pay cash for their prescriptions. These cards are free and they are accessible to people with health insurance and to people without health insurance.

There are various savings programs that negotiate their drug discounts on medications like Xifaxan. Patients are able to obtain those lower costs through their prescription discount cards.

Get Xifaxan Discounts Every Month
Through The Rx Advocates

At The Rx Advocates, our mission is to provide assistance to people with obtaining their prescription medications at an affordable price. We understand how expensive medications can be and paying cash for them is not possible in some cases. There are various patient assistance programs that offer discounts and services that many people are not aware of.

Patient assistance programs are beneficial to people with health insurance and to people without health insurance. These programs make it so that patients are saving hundreds and even thousands of dollars on their prescriptions each month.

If you are interested in learning how The Rx Advocates can benefit you and how you can save money on your monthly prescriptions then contact us today. We can help you afford your medications. We can check to see if you are eligible for our services. We will review your information and determine if you meet the guidelines to receive help from us.

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