Menopause hit harder than you expected. Hot flashes interrupt meetings, night sweats ruin your sleep, and the discomfort affects every part of your day. Your doctor recommended Premphase for hormone replacement therapy, explaining it would manage these symptoms and protect your bone density long-term. You were ready to start treatment until the pharmacy quoted the monthly price. Now you’re weighing whether symptom relief is worth the ongoing expense.
The Rx Advocates specializes in enrolling patients in Patient Assistance Programs (PAPs) that reduce hormone therapy costs for women who qualify based on household income.
What is the Premphase Patient Assistance Program?
Pharmaceutical companies fund programs for patients requiring hormone replacement therapy who meet income-based eligibility requirements. These programs provide Premphase at substantially reduced costs to qualifying applicants, ensuring menopause symptoms don’t go untreated because of financial constraints.
You submit prescription documentation and income verification. Our staff assembles your application, coordinates with your healthcare provider, submits everything to the manufacturer, and tracks approval. Once enrolled, Premphase ships to your home monthly.
We work as a prescription advocacy service that connects women across the country with manufacturer programs offering medications at income-determined rates instead of retail pricing.
How to Qualify
Program eligibility centers on household income and valid prescription:
- Singles earning less than $40,000 yearly
- Couples whose combined annual income is less than $60,000
- Larger families with annual income of less than $100,000
- Valid prescription from licensed healthcare provider
Even if you meet these requirements, approval isn’t guaranteed. The eligibility criteria for patient assistance vary across programs. Don’t hesitate to reach out to us to find out if you qualify.
Cost of Premphase
with The Rx Advocates
The monthly service fee depends on the number of medications you take. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.
The Rx Advocates Can Help Reduce Premphase Costs
You’ll pay a fixed monthly fee based on how many medications you need assistance with. That fee never changes when retail prices increase or fluctuate.
Hormone replacement therapy often continues for years. Our service helps women in various insurance situations: those facing high deductibles, plans with poor prescription coverage, or no insurance coverage at all.
We don’t provide coupons or discount cards. We handle enrollment in pharmaceutical company programs that deliver ongoing medication access at costs well below retail.
Cost of Premphase vs Other Options
$80.00/month
$296.99
* Source: GoodRx.com
Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.
Why Patient Assistance Programs Beat Coupons
Coupons give temporary relief. Patient assistance programs provide lasting solutions.
Coupon limitations
- Pharmacy restrictions: Only accepted at certain locations
- Copay accumulators: May not apply toward your deductible
- Expiration dates: Limited validity period
- Coverage gaps: Often insufficient when medication costs are high
- Redemption requirements: Physical presentation at pharmacy needed
PAP advantages
- Substantial savings: Far exceed typical coupon discounts
- Reliable access: Consistent availability without expiration concerns
- Predictable costs: Your fee stays the same regardless of price changes
- Convenient delivery: Medication ships directly to you
Frequently Asked Questions (FAQ)
We’ve compiled answers to some of the most common questions about Premphase and patient assistance programs.
With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.
- 1 Medication (Premphase only) – $80 per month
- 2 Medications (Premphase + 1 other) – $90 per month
- 3 Medications (Premphase + 2 others) – $100 per month
- 4+ Medications – $110 per month
Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.
Without a patient assistance program, Premphase is expensive. Retail costs fluctuate based on factors patients can’t control.
Several factors influence the final price a patient may pay:
- Dosage: Higher prescribed strengths or quantities cost more
- Location: Prices vary by region due to healthcare and pharmacy pricing differences
- Pharmacy: Each pharmacy sets its own retail structure, which can cause major variations
- Insurance Coverage: Patients with commercial insurance may pay less, while those without coverage often face the full retail cost
This means that two patients could pay very different amounts for the same prescription, depending on where they live, where they buy their medication, and their insurance status.
Most patients meet the requirements when annual household income stays below $40k for individuals, $60k for couples, or $100k for larger families. Since manufacturer requirements can differ, The Rx Advocates assess each case individually to determine eligibility.
The Rx Advocates manage enrollment and monthly refills, coordinating all necessary paperwork with your prescribing physician, submitting completed applications to manufacturers, and arranging medication deliveries to prevent treatment interruptions.
About Premphase
Premphase is a hormone replacement therapy combining conjugated estrogens and medroxyprogesterone used to treat menopausal symptoms.
How it works: Premphase contains both estrogen and progestin. The estrogen relieves hot flashes, night sweats, and vaginal dryness caused by menopause. The progestin protects the uterine lining from overgrowth that can occur with estrogen-only therapy.
Administration: Taken as oral tablets daily following a specific schedule. The therapy involves taking estrogen-only tablets for part of the cycle, then combination tablets. Your doctor will explain the dosing schedule.
Side effects:
- Common: Breast tenderness, headache, nausea, bloating, mood changes
- Serious: Blood clots, stroke, heart attack, breast cancer, uterine cancer
Important warnings: Hormone therapy increases risk of blood clots, stroke, and certain cancers. Your doctor should evaluate your personal risk factors before prescribing. Regular mammograms and pelvic exams are essential during treatment. Inform your doctor if you experience chest pain, sudden vision changes, severe headaches, or unusual vaginal bleeding.
Get Started Today
Menopause symptoms significantly impact quality of life. Untreated symptoms can lead to sleep deprivation, mood disruption, and decreased bone density that increases fracture risk. Stopping treatment prematurely or skipping doses because of cost concerns means suffering through manageable symptoms unnecessarily.
We built this service because hormone therapy shouldn’t be available only to women with excellent insurance. Manufacturer assistance programs exist with allocated funding specifically to help patients who need financial support.
Contact us today to learn how patient assistance programs can help you afford Premphase treatment.
