Prempro Coupon & Assistance Programs

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Authored by Nicole Colwell, / Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: September 8, 2023

Having trouble paying for your Prempro prescription? We understand that for many people, the cost of Prempro can be a serious concern without the backing of insurance coverage, a Prempro coupon, savings card, or patient assistance program. At The Rx Advocates, we’re here to help you navigate this financial challenge. Our aim is to significantly lower your monthly Prempro expenses by assisting you in accessing patient assistance programs provided by pharmaceutical companies. These programs often yield much greater savings compared to a standard Prempro coupon, allowing you to receive the medication you depend on without putting undue strain on your finances.

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Prempro Cost

(using The Rx Advocates)

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30-Day Supply

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Prempro Price

(estimated retail*)

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One Dose Pack

* Source:


Access the Prempro patient assistance program with the Rx Advocates

The Rx Advocates is a patient advocacy program that works with various patient assistance programs to help get the best discounts for patients. We can help people from the first time they get their prescriptions filled until they no longer need it. We do this by working with more than 100 pharmaceutical company patient assistance programs in the United States. This allows us to get discounts for more than 800 FDA-approved medications. Our patients can save a substantial amount of money when they work with us. 

When we work with our patients, they never pay more than our monthly service fee, which ranges between $70-$100. The service fee amount depends on the number of medications a patient needs to obtain every month. One prescription is $70, and the amount increases per medication by $10 up to $100 for four or more. They are delivered right to the patient’s door, free of charge. There are never any hidden fees or surcharges.

We do not have a health insurance plan, prescription drug discount card, or coupons to give to our patients. Instead, we work with patient assistance programs on their behalf to get the best possible discounts. This is a task that can be rather daunting and time-consuming. But at The Rx Advocates, we take over the role of applying for these programs, so our patients do not have to worry about it.

How much does Prempro cost?

As of June 2023, the average retail cost of Prempro is $293.96.

The cost of Prempro can vary based on where the pharmacy is located and their prices for various strengths of this medication. This price is for cash-paying customers and not for people with health insurance. But they may still have to pay a high copay or coinsurance payment in order to obtain their medication.

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Eligibility for Prempro patient assistance programs

There are certain criteria that must be met in order for people to qualify for financial assistance through The Rx Advocates. In order to be eligible for our services, the following income requirements must be met:
  • Individuals need to have an annual income below $40,000.
  • Couples need to have an annual income below $60,000.
  • Large families need to have an annual income below $100,000.

But there are always exceptions and, depending on the patient assistance program, these guidelines can vary. We always encourage people to contact us to do an individual review of their case to find out if they are eligible.

Prempro coupon, discounts, & patient assistance FAQ's

Prempro is a medication that is also sold under the generic name conjugated estrogen-medroxyprogesterone. As we mentioned previously, this medication may be prescribed for women who are going through menopause.

Prempro has two synthetic hormones – estrogen and progesterone – which tend to deplete when women reach menopause, typically at age 50 or above. Many of the symptoms of menopause are troublesome, such as hot flashes and vaginal dryness. Prempro can improve those symptoms. 

Progestin is added to Prempro because it can help to reduce the risk of uterine cancer versus estrogen alone. Some doctors will continue to prescribe this medication for women even after they have gone through menopause. Research has shown that it can help prevent bone loss.

Like any medication, Prempro does have some side effects that women may experience when taking it. Many of them should be mild, and they may go away with continued use of this medication. They may include:

  • An upset stomach
  • Nausea or vomiting
  • Breast tenderness
  • Bloating
  • Weight changes
  • Headaches 

Some serious side effects can occur as well. Patients should talk with their doctors if they experience any of the following:

  • Depression
  • Memory loss
  • Other mood or behavioral health changes
  • Unusual vaginal bleeding
  • Severe stomach pain
  • Persistent nausea or vomiting
  • Yellowing eyes or skin
  • Dark urine

There are many other medications that doctors may prescribe for patients instead of Prempro. They offer similar benefits, even though they are different.

Some of the medications that contain estrogen only include:

For women who need progestin only, Prometrium or Provera may be prescribed. There are also other medications that combine both progestin and estrogen and they are: 

Using a prescription drug coupon to help pay for medication differs from working with a patient assistance program. At The Rx Advocates, we do not provide coupons, but we still feel it is important to know how they work.

When a patient is prescribed Prempro, they will often look online to find the best possible coupons to give them a discount. This might seem like a good solution, but coupons do not always provide the best savings. They often are only valid for one-time use, or they may have even already expired. It is rare to find a coupon that will bring the cost of Prempro down enough to make it affordable for people long-term.

Get Prempro Discounts Every Month
Through The Rx Advocates

At The Rx Advocates, we want to erase the stress that can come with not being able to afford one’s monthly medications. We know how hard it can be to have to pay for medicine out-of-pocket. Too many people are made to choose between their health and covering their monthly bills. We want to change that for as many people as we can.

When our patients work with The Rx Advocates, they enjoy savings on prescription medications like Prempro all year long. We never charge any hidden fees, and we work with people who do not have health insurance and those who do.

Would you like to know more about The Rx Advocates’ program? Contact us today and we will check your eligibility.

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