Authored by Chris Schumacher / Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: April 2025
Treating depression can be a challenging journey, and the high cost of medications like Aplenzin only adds to the struggle. For many patients, financial barriers make it harder to stay consistent with their treatment plan, creating additional stress during an already difficult time.
At The Rx Advocates, we’re dedicated to removing the financial burden by connecting patients with patient assistance programs (PAPs). These programs provide dependable, long-term savings on essential medications like Aplenzin, helping you focus on your health and well-being without the worry of overwhelming costs.

Aplenzin Cost

$80.00/month

Aplenzin Price

$3,398/month
* Source: GoodRx.com
Save on Aplenzin With The Rx Advocates
The Rx Advocates specializes in simplifying access to over 800 FDA-approved medications, including Aplenzin. Through partnerships with more than 100 pharmaceutical companies, we help patients access affordable alternatives to expensive prescriptions.
Our pricing is straightforward:
- 1 Medication (Aplenzin only) – $80 per month
- 2 Medications (Aplenzin + 1 other) – $90 per month
- 3 Medications (Aplenzin + 2 others) – $100 per month
- 4+ Medications – $110 per month
With a one-time enrollment fee of $35 and no hidden charges, we manage the entire process for you, ensuring affordable access to Aplenzin while letting you focus on your recovery.
Why Aplenzin Coupons Aren’t Enough
While Aplenzin coupons may offer temporary relief, they rarely provide a sustainable solution for managing ongoing prescription costs. Here’s why relying on coupons may not be ideal:
- Short-Term Relief: Coupons often expire after a limited number of refills.
- Restricted Use: Some coupons can only be redeemed at specific pharmacies.
- No Insurance Impact: Coupons don’t count toward insurance deductibles or out-of-pocket maximums.
- Unreliable Savings: Finding, managing, and using coupons can be time-consuming and stressful.
Patient assistance programs address these issues, offering a reliable and consistent way to save on your medication.
Aplenzin Cost Breakdown
As of January 2025, the cost for Aplenzin (hydrobromide 174 mg/24 hours) oral tablet, extended release is around $2,140 for a supply of 30 tablets. The cost of Aplenzin can vary depending on the dosage and pharmacy. The following strengths are commonly prescribed:
- 174 mg
- 348 mg
- 522 mg
These costs can add up quickly for patients managing long-term treatment, but patient assistance programs can significantly reduce these expenses, ensuring continued access to this essential medication.
How much will it cost with The Rx Advocates?
If approved, by the Aplenzin Patient Assistance Program, you’ll be charged a fixed monthly service fee. This fee varies depending on the number of medications you qualify for. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
Who Qualifies for Aplenzin Assistance Programs?
Patient assistance programs are designed to help those who face challenges affording their medications. Eligibility criteria typically include:
- Income Requirements: Individuals earning $40,000 or less annually, couples earning $60,000 or less, or families earning $100,000 or less may qualify.
- Insurance Status: These programs are often for patients who are uninsured or underinsured.
- Prescription Requirement: A current prescription for Aplenzin from a licensed healthcare provider is needed.
At The Rx Advocates, we handle every step of the process, from confirming your eligibility to completing the necessary paperwork. To find out if you qualify, click here.
Aplenzin Coupon, Discounts, & Patient Assistance FAQ
Aplenzin (bupropion hydrobromide) is an extended-release antidepressant used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It works by affecting neurotransmitters in the brain, helping to improve mood and energy levels.
Aplenzin is typically taken once daily and can be taken at various dosages. Consistent use as prescribed by your healthcare provider is key to effectively managing depression and achieving better mental health outcomes.
If Aplenzin isn’t the right fit for your treatment, other antidepressants may be available, such as:
- Wellbutrin XL (bupropion)
- Zyban (bupropion)
- Effexor XR (venlafaxine)
- Cymbalta (duloxetine)
Your healthcare provider can help determine the best medication based on your unique needs and medical history.
Aplenzin coupons are often marketed as a way to reduce costs, but they typically offer short-term discounts and may not cover the long-term expenses of your treatment. Coupons often expire after a limited number of uses and may only be accepted at specific pharmacies.
Patient assistance programs are a more reliable alternative for those looking for consistent savings. They provide ongoing affordability for qualified patients.
Affordable Aplenzin With The Rx Advocates
At The Rx Advocates, we believe that the cost of medication should never prevent you from managing your mental health. By connecting patients with patient assistance programs, we provide an affordable and sustainable way to access essential medications like Aplenzin.
Whether you’re uninsured or underinsured, we manage the entire process for you so you can focus on your recovery without the stress of high prescription costs. If you’re ready to save on Aplenzin, contact us today. Let us help you access the medications you need to feel better and take control of your health.