Aplenzin Patient Assistance Program

Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: October 17, 2025

Treating depression can be a challenging journey, and the high cost of medications like Aplenzin only adds to the struggle. For many patients, financial barriers make it harder to stay consistent with their treatment plan, creating additional stress during an already difficult time.

At The Rx Advocates, we’re dedicated to removing the financial burden by connecting patients with Patient Assistance Programs (PAPs). These programs provide dependable, long-term savings on essential medications like Aplenzin, helping you focus on your health and well-being without the worry of overwhelming costs.

How to Qualify

Patient assistance programs are designed to help those who face challenges affording their medications. Eligibility criteria typically include:

  • Individuals earning $40,000 or less annually
  • Couples earning $60,000 or less annually
  • Families earning $100,000 or less annually
  • Current prescription for Aplenzin from licensed healthcare provider
  • U.S. residency

We handle every step of the process, from confirming your eligibility to completing necessary paperwork. Call us to see if you qualify.

Pricing

Cost of Aplenzin
with The Rx Advocates

The monthly service fee depends on the number of medications you take. For example:

1 Medication

$80 / Month

2 Medications

$90 / Month

3 Medications

$100 / Month

4 Medications

$110 / Month

NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.

The Rx Advocates Can Help Reduce Aplenzin Costs

We are not a coupon, savings card, or insurance plan. We connect patients with PAPs to get them medications at affordable prices.

Our pricing is straightforward. With a one-time enrollment fee of $35 and no hidden charges, we manage the entire process for you, ensuring affordable access to Aplenzin while letting you focus on your recovery.

Depression treatment requires consistency. We handle application paperwork, documentation requirements, and renewal processes. Working with you and your healthcare provider, we gather required materials and submit them properly. Once approved, antidepressant medication arrives consistently each month.

Cost of Aplenzin vs Other Options

The Rx Advocates logo w text alt 5
Aplenzin Cost
(using The Rx Advocates)
Dollar sign logo
30-Day Supply
$80.00/month
Goodrx logo
Aplenzin Price
(estimated retail*)
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One Dose Pack
$3265

* Source: GoodRx.com

Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.

Why Patient Assistance Programs Beat Coupons

While Aplenzin coupons may offer temporary relief, they rarely provide a sustainable solution for managing ongoing prescription costs. PAPs address these issues, offering reliable and consistent ways to save.

Coupon limitations

  • Short-term relief: Coupons often expire after limited number of refills
  • Restricted use: Some coupons can only be redeemed at specific pharmacies
  • No insurance impact: Coupons don’t count toward insurance deductibles or out-of-pocket maximums
  • Unreliable savings: Finding, managing, and using coupons can be time-consuming and stressful

PAP advantages

  • Dependable savings: Long-term savings on essential medications
  • Straightforward pricing: Fixed monthly fees with no hidden charges
  • Full management: We manage entire process for you
  • Focus on recovery: Let you concentrate on health without worry of overwhelming costs

Frequently Asked Questions (FAQ)

Patients managing depression commonly ask these questions about Aplenzin costs and assistance.

With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.

  • 1 Medication (Aplenzin only) – $80 per month
  • 2 Medications (Aplenzin + 1 other) – $90 per month
  • 3 Medications (Aplenzin + 2 others) – $100 per month
  • 4+ Medications – $110 per month

Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.

Cost can vary depending on dosage and pharmacy:

  • 174 mg: Common prescribed strength
  • 348 mg: Common prescribed strength
  • 522 mg: Common prescribed strength

These costs can add up quickly for patients managing long-term treatment, but Patient Assistance Programs (PAPs) can significantly reduce these expenses, ensuring continued access to essential medication.

Individuals earning $40,000 or less, couples earning $60,000 or less, or families earning $100,000 or less annually may qualify. Programs are often for patients who are uninsured or underinsured. Contact us to find out if you qualify.

We believe that the cost of medication should never prevent you from managing your mental health. By connecting patients with PAPs, we provide affordable and sustainable ways to access essential medications. Whether you’re uninsured or underinsured, we manage the entire process so you can focus on recovery without stress of high prescription costs.

About Aplenzin

Aplenzin (bupropion hydrobromide) is an extended-release antidepressant used to treat major depressive disorder and seasonal affective disorder.

How it works: Affects neurotransmitters in the brain, helping to improve mood and energy levels.

Administration: Typically taken once daily and can be taken at various dosages. Consistent use as prescribed by your healthcare provider is key to effectively managing depression and achieving better mental health outcomes.

Side effects:

  • Common: Dry mouth, nausea, insomnia, headache, dizziness
  • Serious: Seizures, changes in mood or behavior, severe allergic reactions

Important warnings: May increase risk of suicidal thoughts, especially in young adults. Contact your healthcare provider immediately if you experience worsening depression or unusual changes in behavior.

Get Started Today

Financial barriers make it harder to stay consistent with treatment plans, creating additional stress during already difficult times. The cost of medication should never prevent you from managing your mental health.

By connecting you with PAPs, we provide an affordable and sustainable way to access essential medications like Aplenzin. If you’re ready to save on Aplenzin, contact us today.

Let us help you access medications you need to feel better and take control of your health. Call us today.

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