Without proper insurance, Entresto costs can create major financial obstacles for patients managing heart failure. Through manufacturer Patient Assistance Programs, eligible patients may pay a low, fixed monthly fee. The Rx Advocates handle the entire process so you can stay on treatment without financial stress.
What is the Entresto Patient Assistance Program?
Entresto’s Patient Assistance Program is supported by the drug’s manufacturer to help qualifying patients secure their medication at reduced or no cost. Discount cards and coupons may lower prices temporarily, but PAPs offer dependable, long-term financial support for individuals requiring continuous heart failure therapy. The Rx Advocates help patients navigate application steps, confirm program qualifications, and maintain enrollment in the Entresto PAP.
How to Qualify
Qualifying for patient assistance program benefits depends on meeting certain income and residency criteria. These program standards aim to support people facing financial challenges and keep essential treatments accessible to everyone in need.
Typical requirements to qualify include:
- Individuals qualify if they earn up to $40,000 annually
- Couples qualify if they earn up to $60,000 annually
- Larger families qualify if they earn up to $100,000 annually
- U.S. residency and a valid prescription
Keep in mind: each program sets different standards. Our team can evaluate your specific situation and assist with the application process.
Cost of Entresto
with The Rx Advocates
The monthly service fee depends on the number of medications you take. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.
The Rx Advocates Can Help Reduce Entresto Costs
The Rx Advocates link patients with manufacturer-supported programs from more than 100 pharmaceutical companies. This network grants access to over 800 FDA-approved prescription medications, with Entresto included among the nation’s frequently prescribed drugs.
We aren’t a coupon service, insurance provider, or discount card company. Our specialists manage the complete enrollment experience by assembling required forms, coordinating with your doctor, and submitting finalized applications to manufacturers. We conduct consistent follow-ups to confirm processing and arrange monthly refills to maintain uninterrupted treatment.
Cost of Entresto vs Other Options
$80.00/month
$838.53
* Source: GoodRx.com
Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.
Why PAPs Are Better Than Coupons
Discount cards and coupons could provide near-term Entresto savings, but these options carry notable drawbacks that compromise their usefulness for ongoing medication requirements. Manufacturer-sponsored Patient Assistance Programs deliver steady, continuous financial support and reliable prescription access.
Disadvantages of coupons
- Restrictions: Typically accepted only at select pharmacies or during limited periods
- Copay Accumulators: Can block coupons from applying toward your insurance out-of-pocket maximum or deductible
- Expiration Dates: Coupons expire and demand regular replacement
- Limited Coverage: Most coupons still result in significant patient costs
Advantages of PAP through The Rx Advocates
- Fixed Monthly Cost: Predictable fees unaffected by retail price increases
- No Expiration: Continued access throughout your qualification period
- Direct From Manufacturer: Dependable monthly medication supply from the source
- Broad Support: Includes over 800 FDA-approved prescription medications
Frequently Asked Questions (FAQ)
See answers to common questions about Entresto and patient assistance programs listed below.
With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.
- 1 Medication (Entresto only) – $80 per month
- 2 Medications (Entresto + 1 other) – $90 per month
- 3 Medications (Entresto + 2 others) – $100 per month
- 4+ Medications – $110 per month
Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.
Right now, Entresto typically costs around $650-$700 for a 30-day supply at retail pharmacies.
Multiple factors influence final pricing:
- Dosage: Available in various strengths (24/26 mg, 49/51 mg, 97/103 mg tablets)
- Location: Geographic healthcare pricing variations affect costs
- Pharmacy: Individual pharmacies set their own retail pricing structures
- Insurance Coverage: Commercially insured patients generally pay less than uninsured patients
Most patients qualify when annual household income falls below $40,000 for individuals, $60,000 for couples, or $100,000 for families with multiple members. Since each manufacturer uses different standards, The Rx Advocates review applications individually.
The Rx Advocates handle enrollment and refill coordination by gathering necessary paperwork with your healthcare provider, forwarding applications to manufacturers, and scheduling medication deliveries to ensure treatment continuity.
About Entresto
Entresto (sacubitril/valsartan) is a combination medication containing an ARB (angiotensin receptor blocker) and a neprilysin inhibitor. It is primarily prescribed for adults with chronic heart failure to reduce the risk of cardiovascular death and hospitalization.
Mechanism of action: Entresto works through two mechanisms; valsartan blocks angiotensin II receptors to relax blood vessels and lower blood pressure, while sacubitril inhibits neprilysin to increase beneficial peptides that help the heart pump more effectively.
Additional uses: Entresto is also prescribed for certain pediatric patients with heart failure and for adults with symptomatic heart failure with preserved ejection fraction.
Form & administration: Administered by the patient as an oral tablet taken twice daily. Available in 24/26 mg, 49/51 mg, and 97/103 mg combination strengths. Should be taken consistently with or without food.
Side effects:
- Common: low blood pressure, high potassium levels, cough, dizziness, kidney problems.
- Serious: angioedema (swelling of face, lips, tongue, throat), kidney dysfunction, hyperkalemia.
- Warning: do not take with ACE inhibitors or within 36 hours of stopping ACE inhibitor therapy; contraindicated in patients with history of angioedema; not for use during pregnancy; regular monitoring of kidney function and potassium levels required.
Get Started Today
The Rx Advocates strive to eliminate cost obstacles that prevent patients from obtaining necessary medications. If Entresto expenses are creating barriers to your heart failure treatment, our specialists can assist with patient assistance program qualification and maintain ongoing prescription support.
Get in touch today to determine if you qualify and start lowering your Entresto costs.
