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Linzess Patient Assistance Program

Searching for ways to afford your Linzess prescription? Many patients face high out-of-pocket costs that make medication access difficult. At The Rx Advocates, we help you gain affordable access through manufacturer patient assistance programs. These programs provide better long-term savings than coupons or discount cards. Through manufacturer Patient Assistance Programs, eligible patients may pay a low, fixed monthly fee. The Rx Advocates handle the entire process so you can stay on treatment without financial stress.

Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS

Last Updated: April 7, 2026

What is the Linzess
Patient Assistance Program?

The Linzess Patient Assistance Program is established by the pharmaceutical manufacturer to assist qualifying individuals in obtaining their medication affordably. Though coupons may seem helpful, patient assistance programs deliver more substantial and sustainable savings for long-term treatment.

The Rx Advocates help patients apply to these manufacturer programs, complete required applications, and maintain active enrollment in the Linzess PAP.

Eligibility Requirements

Specific income thresholds must be met to qualify for patient assistance programs. Our team evaluates your financial circumstances against program requirements.

Typical requirements to qualify include:

  • Individuals qualify if they earn up to $40,000 annually
  • Couples qualify if they earn up to $60,000 annually
  • Larger families qualify if they earn up to $100,000 annually
  • U.S. residency and a valid prescription

These criteria are designed to make programs accessible to people struggling with prescription drug costs. Contact us and we can evaluate your specific situation to help determine if you qualify.

Cost of Linzess
with The Rx Advocates

The monthly service fee depends on the number
of medications you take. For example:

1 Medication
$80 / Month
2 Medications
$90 / Month
3 Medications
$100 / Month
4 Medications
$110 / Month

In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time

Pharmacy Prices
Prices are estimated and may vary by pharmacy and location. Price data is based on publicly available pharmacy pricing information.
Retail price
$465.85
WalgreensPrice with a coupon
$298.65
CVS PharmacyPrice with a coupon
$309.27
CostcoPrice with a coupon
$320.21
WalmartPrice with a coupon
$299.23
Walmart Neighborhood MarketPrice with a coupon
$299.23
Target (CVS)Price with a coupon
$309.27
Walgreens Specialty PharmacyPrice with a coupon
$298.65
Navarro Discount PharmacyPrice with a coupon
$309.27
Capsule PharmacyPrice with a coupon
$565.46
PublixPrice with a coupon
$299.49
Patient Assistance Program 30-Day Supply with The Rx Advocates
$80

The Rx Advocates can help
reduce Linzess costs

The Rx Advocates work closely with many US pharmaceutical companies that offer patient assistance programs. We help patients access the top 100 prescribed medicines in the US and over 800 FDA-approved drugs with no hidden costs or fees.

We are not a health insurance provider, nor do we provide savings cards, discount cards, or coupons. Our team specializes in completing applications for patient assistance programs on your behalf. We handle all paperwork, coordinate with your healthcare provider, and submit applications to manufacturers. We follow up to confirm approvals and arrange monthly refills so your medication arrives consistently.

Tired of coupon restrictions? While coupons can help lower medication costs, they come with significant limitations that make them less effective than patient assistance programs.

Disadvantages
of coupons

  • Restrictions: Often limited to certain pharmacies, timeframes, or specific insurance plans
  • Copay Accumulators: May not count toward your out-of-pocket maximum due to insurance copay accumulators
  • Expiration Dates: Every coupon expires, becoming useless after that date
  • Limited Coverage: Typically leave patients responsible for significant portions of medication costs

Advantages of PAP
through The Rx Advocates

  • Fixed Monthly Cost: Stable pricing unaffected by retail cost changes
  • No Expiration: Ongoing access maintained throughout your qualification period
  • Direct From Manufacturer: Consistent medication delivery from the source
  • Broad Support: Access to over 800 FDA-approved medications

Cost of Linzess vs Other Options

Comparison

Abilify Maintena Cost
(using The Rx Advocates)

$80 / Month

30-Day Supply

Abilify Maintena Price
(estimated retail*)
$465.85One Dose Pack

Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location

Frequently Asked Questions
(FAQ)

How much does Linzess cost with The Rx Advocates?

With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.

  • 1 Medication (Linzess only) – $80 per month
  • 2 Medications (Linzess + 1 other) – $90 per month
  • 3 Medications (Linzess + 2 others) – $100 per month
  • 4+ Medications – $110 per month

Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.

How much does Linzess cost without assistance?

Linzess typically costs around $683.48 for a 30-day supply at retail pharmacies.

However, price variations depend on multiple factors:

  • Dosage: Available in 72 mcg, 145 mcg, and 290 mcg capsules
  • Location: Patient’s geographic area influences pricing
  • Pharmacy: Each pharmacy location sets its own costs
  • Insurance Coverage: Whether health insurance covers prescription drug costs significantly affects out-of-pocket expenses
Do I qualify for the Linzess patient assistance program?

General eligibility guidelines include earning less than $40,000 annually for singles, combined annual income under $60,000 for couples, and household income below $100,000 for large families. Contact us so we can evaluate your specific situation and help determine if you qualify.

How will The Rx Advocates help me through the program and refills?

The Rx Advocates manage enrollment and refills by gathering required documentation with your prescriber, submitting applications to the manufacturer, and coordinating medication deliveries to grant consistent access to your prescription.

About Linzess

Linzess (linaclotide) is a guanylate cyclase-C agonist medication. It is primarily prescribed for adults with chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C).

Mechanism of action: Linzess works by increasing intestinal secretions to soften stools and improve bowel movements, reducing abdominal pain and discomfort associated with constipation.

Additional uses: Linzess is also approved for treating functional constipation (FC) in children and adolescents aged 6-17.

Form & administration: Administered by the patient as an oral capsule taken once daily. Available in 72 mcg, 145 mcg, and 290 mcg strengths. Should be taken on an empty stomach at least 30 minutes before the first meal of the day.

Side effects:

  • Common: diarrhea, abdominal pain, gas, bloating.
  • Serious: severe diarrhea, dehydration.
  • Warning: not for children under age 6 (caused fatal dehydration in young mice in animal studies); take on empty stomach for proper absorption.

Conclusion

Helping people obtain their medications at affordable prices is the goal of The Rx Advocates. We understand that high prescription drug costs prevent many from accessing needed medications. If Linzess costs are creating barriers to treatment, we can connect you with patient assistance programs and provide ongoing support.

Contact us right away and our team can review your specific situation to help determine if you qualify for patient assistance programs.