Authored by Chris Schumacher / Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: July 2025
Ziana (clindamycin phosphate and tretinoin gel) is a topical prescription medication designed to treat acne vulgaris in patients 12 years and older. This combination therapy pairs an antibiotic with a retinoid to target both bacterial infection and abnormal skin cell turnover that contribute to acne formation. Patients apply Ziana once daily in the evening as directed by their dermatologist.
Acne treatment shouldn’t break your budget, especially when dealing with a condition that already affects self-confidence. Ziana comes with a significant price tag that can make consistent treatment difficult to maintain. Many patients search for manufacturer coupons or pharmacy discounts to make treatment more affordable. While these options might provide initial savings, they often include limitations that make long-term treatment planning challenging.
The Rx Advocates help patients connect with patient assistance programs that deliver more consistent and meaningful financial support.
Ziana Cost
$80.00/month
Ziana Price
$109.46/month
* Source: GoodRx.com
Save on Ziana With The Rx Advocates
The Rx Advocates are well-versed in helping patients access over 800 FDA-approved medications, including Ziana, through trusted patient assistance programs. We work with over 100 pharmaceutical companies to secure meaningful savings for those who qualify.
Our pricing is simple and affordable:
- 1 Medication (Ziana only) – $80 per month
- 2 Medications (Ziana + 1 other) – $90 per month
- 3 Medications (Ziana + 2 others) – $100 per month
- 4+ Medications – $110 per month
With a one-time enrollment fee of $35 and no surprise fees, we handle all the heavy lifting, from application submission to follow-ups, so you can focus on your treatment without unnecessary stress.
Issues with Ziana Discount Coupons
Manufacturer coupons for Ziana might look promising at first, but they frequently come with restrictions that limit their long-term value:
- Limited duration periods that typically expire within a few months
- Pharmacy network limitations that may not include your regular location
- Government insurance exclusions
- Benefit maximums that may not cover the full treatment period
- Restrictions that prevent coupon savings from counting toward insurance deductibles
Since acne treatment often requires several months of consistent use to see optimal results, these coupon limitations can interrupt treatment progress when programs end unexpectedly.
How We Help with Ziana Patient Assistance
Our approach centers on helping patients connect with patient assistance programs offered directly by pharmaceutical manufacturers. These programs may provide ongoing support for eligible patients based on their financial circumstances and insurance coverage situations.
We handle every step of the application process from initial evaluation through program maintenance. This includes managing application procedures, working with dermatology practices, and helping with renewals to support continued treatment access.
How much will it cost with The Rx Advocates?
If approved, by the Ziana Patient Assistance Program, you’ll be charged a fixed monthly service fee. This fee varies depending on the number of medications you qualify for. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
Eligibility Criteria for Patient Assistance Programs
Patient assistance programs use detailed qualification standards that go beyond simple income requirements. Each application undergoes individual review, with decisions based on multiple factors that may not be immediately clear to applicants.
Programs may consider criteria such as:
- Insurance coverage status and potential gaps in Ziana treatment coverage
- Annual household income, often with thresholds around $40,000 for individuals or $100,000 for families
- U.S. citizenship or legal residency status
- Active prescription status with valid Ziana orders from licensed dermatologists
- Documentation of financial need
We can review your specific situation and determine if you qualify.
Full-Service Application and Renewal Management
Dealing with acne often involves multiple dermatology appointments, treatment adjustments, and skincare routine modifications. Complex assistance program paperwork shouldn’t add stress to your treatment journey.
We manage these administrative responsibilities for you:
- Conducting eligibility reviews across available programs
- Collecting and preparing all required documentation and forms
- Working with your dermatologist’s office to obtain necessary medical information
- Completing and submitting applications with all supporting materials
- Tracking application status and communicating with program representatives
- Handling renewal processes and deadlines to maintain program participation
Acne Treatment Alternatives
Ziana is a highly effective medication in the treatment of moderate acne, with many patients experiencing significant improvement in inflammatory and non-inflammatory lesions within 12 weeks of consistent use.
However, acne treatment approaches vary based on individual skin characteristics, severity levels, and previous treatment responses. Your dermatologist evaluates multiple factors when selecting the most appropriate therapy.
Alternative options for Ziana exist, but speak to your doctor about treatment options first to determine if that’s the right course. Your dermatologist has the clinical expertise to choose the most suitable treatment strategy based on your specific skin condition and medical history.
Ziana Coupon, Discounts, & Patient Assistance FAQ
Yes, having insurance doesn’t prevent you from potentially qualifying for patient assistance programs. Many insured patients still face high out-of-pocket costs due to deductibles, copayments, or limited dermatology medication coverage.
Eligibility varies by program for government insurance beneficiaries. Medicaid recipients typically cannot receive assistance since Medicaid covers prescription medications. Medicare patients may have limited options depending on their specific coverage and program guidelines.
Savings differ based on the program and your individual financial situation. Some programs offer substantial cost reductions, while others may provide the medication at reduced rates for patients meeting specific financial criteria.
Most patient assistance programs review applications within four to six weeks of receiving complete submissions with all required documentation.
While you can apply independently, our experience with program requirements helps ensure applications include all necessary information and meet submission guidelines. We also manage ongoing renewal requirements to help maintain program participation.
No, patient assistance programs exclusively provide brand-name medications. Generic alternatives to Ziana are not currently available in the United States.
If you’re declined by all programs we work with, we provide a refund of your monthly service fee. Our initial $35 enrollment fee covers evaluation and application preparation costs and is non-refundable.
Start Your Ziana Assistance Application
Managing acne requires patience, consistency, and often multiple treatment approaches to find what works best for your skin. Financial barriers shouldn’t prevent you from accessing prescribed treatments that could improve your condition.
Patient assistance programs have helped thousands of patients continue their dermatology treatments when insurance coverage wasn’t sufficient. These programs can provide important financial relief that enables consistent treatment and better outcomes.
Contact The Rx Advocates at 844-559-8332 or visit our website to learn about your options. Our team is ready to review your situation and help with the application process for available programs.
