Xiidra Patient Assistance Program

Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: April 7, 2026

Xiidra Patient Assistance Program

Searching for ways to afford your Xiidra prescription? Many people rely on this medication to manage dry eye symptoms, but affording it each month can be challenging without adequate insurance coverage. At The Rx Advocates, we help patients access manufacturer patient assistance programs that provide substantial savings beyond what coupons or copay savings cards can offer. Through these programs, eligible patients may pay a low, fixed monthly fee. We handle the entire process so you can stay on treatment without financial stress.

Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS

Last Updated: April 7, 2026

What is the Xiidra
Patient Assistance Program?

The Xiidra Patient Assistance Program (PAP) is offered by the pharmaceutical company that manufactures Xiidra to help qualifying patients obtain their medication affordably. Coupons might seem convenient, but they come with restrictions on uses, expiration dates, and refill limits.

PAPs deliver consistent, ongoing financial support for individuals requiring long-term dry eye treatment. We connect patients to these manufacturer programs, navigate the application process, and help maintain active enrollment in the Xiidra PAP.

Eligibility Requirements

If you’re considering using a Xiidra coupon to save money on your prescription medication, it’s important to understand its limitations. Xiidra coupons may come with restrictions on the number of uses, expiration dates, or the number of refills allowed. It’s also possible that some pharmacies may not accept the coupon, and it may not always provide the best possible price for the medication. As such, it’s important to carefully evaluate the benefits and drawbacks of using a Xiidra coupon and explore alternative cost-saving options, such as pharmacy discount programs or patient assistance programs, to determine the most effective approach for your needs.

Household income levels determine if you qualify for patient assistance programs. Our team examines your specific circumstances to identify qualifying opportunities.

Typical requirements to qualify include:

  • Individuals qualify if they earn up to $40,000 annually
  • Couples qualify if they earn up to $60,000 annually
  • Larger families qualify if they earn up to $100,000 annually
  • U.S. residency and a valid prescription

Requirements vary between pharmaceutical companies. Contact us right away so we can check the possibilities for yourself or your family.

Cost of Xiidra
with The Rx Advocates

The monthly service fee depends on the number
of medications you take. For example:

1 Medication
$80 / Month
2 Medications
$90 / Month
3 Medications
$100 / Month
4 Medications
$110 / Month

In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time

Pharmacy Prices
Prices are estimated and may vary by pharmacy and location. Price data is based on publicly available pharmacy pricing information.
Retail price
$878.14
WalgreensPrice with a coupon
$755.64
CVS PharmacyPrice with a coupon
$753.61
CostcoPrice with a coupon
$826.04
WalmartPrice with a coupon
$771.87
Walmart Neighborhood MarketPrice with a coupon
$771.87
Target (CVS)Price with a coupon
$753.61
Walgreens Specialty PharmacyPrice with a coupon
$755.64
Navarro Discount PharmacyPrice with a coupon
$753.61
Capsule PharmacyPrice with a coupon
$758.59
PublixPrice with a coupon
$757.59
Patient Assistance Program 30-Day Supply with The Rx Advocates
$80

The Rx Advocates can help
reduce Xiidra costs

The RX Advocates work with over 100 United States-based pharmaceutical companies’ patient assistance programs. Through these partnerships, patients gain access to over 800 FDA-approved medications, including the top 100 most prescribed drugs in the U.S.

We’re not a prescription discount card plan, insurance company, or coupon service. Our team knows how to navigate pharmaceutical assistance programs to help people get needed medications at affordable prices. We handle all paperwork, coordinate with your healthcare provider, and submit applications to manufacturers. Regular follow-ups ensure approvals are processed and monthly refills arrive on schedule.

Considering a Xiidra coupon for savings? Understanding the limitations is essential before relying on them. Patient assistance programs provide more effective, sustainable solutions than coupons.

Disadvantages
of coupons

  • Restrictions: Often have limits on number of uses, refills allowed, or which pharmacies accept them
  • Copay Accumulators: May not count toward insurance out-of-pocket maximums
  • Expiration Dates: Lose validity after expiration, requiring constant replacement searches
  • Limited Coverage: May not always provide the best possible price for medication

Advantages of PAP
through The Rx Advocates

  • Fixed Monthly Cost: Pricing remains stable regardless of retail cost fluctuations
  • No Expiration: Access maintained for the entire qualification period
  • Direct From Manufacturer: Medication delivered consistently from the pharmaceutical source
  • Broad Support: Coverage includes over 800 FDA-approved medications

Cost of Xiidra vs Other Options

Comparison

Abilify Maintena Cost
(using The Rx Advocates)

$80 / Month

30-Day Supply

Abilify Maintena Price
(estimated retail*)
$878.14One Dose Pack

Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location

Frequently Asked Questions
(FAQ)

[acf_faq]

About Xiidra

Xiidra (lifitegrast ophthalmic solution) is a lymphocyte function-associated antigen-1 (LFA-1) antagonist eye drop. It is primarily prescribed for adults to treat signs and symptoms of dry eye disease (DED).

Mechanism of action: Xiidra works by blocking inflammation that contributes to dry eye symptoms, helping to reduce both the signs and symptoms of dry eye disease.

Additional uses: Xiidra is specifically approved for treating dry eye disease in adults. It has not been tested in children under 17 or in pregnant women.

Form & administration: Administered by the patient as eye drops in single-use foil pouches. One drop in each affected eye every 12 hours (twice daily). Remove contact lenses before application and wait 15 minutes before reinserting. Do not save leftover solution from single-use droppers.

Side effects:

  • Common: eye irritation, discomfort, blurred vision, unusual taste in mouth.
  • Serious: severe allergic reactions (rare).
  • Warning: not for patients allergic to any ingredients; store at room temperature (68-77°F); keep in foil pouch to protect from light until use; throw away any leftover solution after use.

Conclusion

Getting patients the monthly medications they need to stay healthy at reasonable prices is our goal. If Xiidra costs are making it difficult to manage your dry eye disease, we can connect you with patient assistance programs and provide continued support.

Contact our team today so we can review your situation and find out if you qualify to start saving today!