Orilissa Patient Assistance Program

Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: October 15, 2025

Endometriosis pain disrupts work, relationships, and daily activities. When Orilissa costs force you to skip doses, symptoms return and quality of life plummets. 

Financial barriers shouldn’t determine whether you manage pain effectively. The Rx Advocates help by linking women to Patient Assistance Programs (PAPs) that make endometriosis treatment affordable. We handle the paperwork so you can focus on pain relief.

What is the Orilissa Patient Assistance Program?

Drug manufacturers fund patient assistance programs for women struggling to afford endometriosis medications. The Orilissa program delivers continuous treatment access instead of short-term coupon savings.

We build direct links between patients and these programs. Working with you and your gynecologist, we gather necessary documents and submit complete applications. We monitor status through approval. Once enrolled, we organize refills to maintain steady pain management. Our network includes over 100 companies whose programs cover more than 800 FDA-approved medications.

Income requirements help but don’t guarantee acceptance since companies review individually. We ensure submissions are accurate and thorough.

How to Qualify

Eligibility depends on yearly household income and U.S. residency. We review your finances against program standards to see if you meet their criteria.

To get started with us, people can qualify if they are:

  • Single and earning less than $40,000 yearly
  • A couple whose combined annual income is less than $60,000
  • A larger family with annual income less than $100,000
  • U.S. resident with valid prescription

Eligibility rules can sometimes change depending on the program. Don’t hesitate to reach out so we can find out if you qualify.

Pricing

Cost of Orilissa
with The Rx Advocates

The monthly service fee depends on the number of medications you take. For example:

1 Medication

$80 / Month

2 Medications

$90 / Month

3 Medications

$100 / Month

4 Medications

$110 / Month

NOTE: In addition to our monthly service fee, we charge a one-time enrollment fee of $35.
Our service is month-to-month, so if you’re not happy with it, you may cancel at any time.

The Rx Advocates Can Help Reduce Orilissa Costs

We’re not a coupon service, insurance plan, or discount card. Our distinction lies in our dedication to linking people to patient assistance programs by handling all paperwork.

Partnering with you and your medical team, we collect application materials and forward them to programs. We stay in touch to confirm documents move through processing. After approval, we handle refills so medication arrives consistently. We arrange for delivery right to your doorstep every month.

You’ll pay a $35 enrollment fee, then monthly charges based on prescription count. Our pricing stays consistent no matter how retail prices fluctuate. We don’t believe in hidden fees or sudden cost spikes.

Cost of Orilissa vs Other Options

The Rx Advocates logo w text alt 5
Orilissa Cost
(using The Rx Advocates)
Dollar sign logo
30-Day Supply
$80.00/month
Goodrx logo
Orilissa Price
(estimated retail*)
Dollar sign logo
One Dose Pack
$1458.08

* Source: GoodRx.com

Last Updated: September 29, 2025. Actual retail prices may vary by pharmacy and location.

Why PAPs Are Better Than Coupons

Coupons offer short-term savings but include significant limitations. Patient assistance programs provide sustainable solutions.

Disadvantages of coupons

  • Usage restrictions: Limited in where and how they can be used
  • Copay accumulators: Might not count toward out-of-pocket maximums
  • Time limits: Expiration dates render them useless
  • Insufficient coverage: Medication remains expensive even with coupons

Advantages of PAPs through The Rx Advocates

  • Simple pricing: Fixed monthly costs
  • Long-term savings: More stable than coupon programs
  • Expert guidance: We help you sidestep high out-of-pocket costs
  • Peace of mind: Consistent access without hefty expenses

Frequently Asked Questions (FAQ)

Women managing endometriosis pain often ask these questions about Orilissa costs and program eligibility.

With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered.

  • 1 Medication (Orilissa only) – $80 per month
  • 2 Medications (Orilissa + 1 other) – $90 per month
  • 3 Medications (Orilissa + 2 others) – $100 per month
  • 4+ Medications – $110 per month

Importantly, there are no hidden fees, and prices remain consistent even if retail costs fluctuate.

Actual price fluctuates based on:

  • Location: Where you live
  • Dosage: Strength prescribed by your physician
  • Pharmacy: Local store pricing
  • Insurance: Whether coverage includes prescription medications

For many, the combination of these variables makes affording Orilissa a real challenge.

Singles earning under $40,000 yearly, couples below $60,000 combined, and larger families under $100,000 annually typically qualify. Our team is here to be your guide. Get in touch immediately to determine your eligibility.

We handle everything to ensure you have constant supply. Application prep. Doctor coordination. Program submission. Approval tracking. After enrollment, we manage refills and delivery without extra charge. No trips to the pharmacy needed.

About Orilissa

Orilissa (elagolix) is prescribed for moderate to severe endometriosis pain in women and for treating uterine fibroids.

How it works: Functions as a gonadotropin-releasing hormone antagonist, reducing production of certain hormones that cause endometriosis symptoms.

Form: Oral tablet. Dosages prescribed based on symptom severity and patient response.

Side effects:

  • Common: hot flashes, headaches, mood changes, nausea
  • Serious: bone density loss, liver injury, suicidal thoughts

Important details: Understanding the mechanism, uses, and potential side effects is crucial in making an informed decision. If you’re considering Orilissa for endometriosis or gynecological conditions, consult your healthcare provider to determine the best treatment plan tailored to your needs.

Get Started Today

Endometriosis pain worsens when treatment gets interrupted. Skipping Orilissa because of cost allows symptoms to return, disrupting work and personal life.

We manage patient assistance applications to make Orilissa affordable. Once approved, medication delivers to your door monthly at stable pricing.

Ready for relief without the financial burden? It’s time to reach out and see if you’re eligible for our program.

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