The blood glucose meter is on the table next to the cinnamon

Does Cinnamon Interact with Diabetes Medications Like Ozempic or Jardiance?

Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: October 8, 2025

When you’re managing Type 2 diabetes, a condition that affects more than 38 million people in the United States, questions about what you can safely combine with your medications naturally arise. You may have heard about cinnamon as a supplement and wondered whether it’s safe to use alongside your prescribed treatments, such as Ozempic or Jardiance.

This concern makes perfect sense. Managing diabetes involves careful attention to how different factors affect your blood sugar levels, and adding anything new to your routine warrants thoughtful consideration. Obtaining accurate, evidence-based information about these interactions is crucial for making informed decisions about your healthcare.

Understanding How Medications like Ozempic & Jardiance Work

Before examining potential interactions, it is helpful to understand how Ozempic and Jardiance work in the body. These medications work through different mechanisms to help control your blood sugar levels, and understanding these processes helps explain why certain interactions might or might not occur.

Ozempic

Ozempic contains semaglutide, which belongs to a class of medications called GLP-1 receptor agonists. This medication mimics a hormone your body naturally produces to help regulate blood sugar. It stimulates insulin release when your blood sugar is elevated, slowing digestion to prevent rapid spikes after meals, and reducing the amount of glucose your liver produces. The medication also affects your appetite and how quickly food moves through your digestive system.

These combined effects help maintain more stable blood sugar levels throughout the day. The medication works best when taken consistently at the same time each week, allowing your body to maintain steady levels of the active ingredient.

Jardiance

Jardiance takes a different approach to blood sugar control. It contains empagliflozin and belongs to a class called SGLT2 inhibitors. This medication works by preventing your kidneys from reabsorbing glucose back into your bloodstream. Instead, the excess glucose is eliminated through your urine, which is why some people notice increased urination when they start taking Jardiance.

What makes Jardiance particularly effective is that it doesn’t rely on your body’s insulin production to work effectively. This mechanism makes it useful for people at various stages of Type 2 diabetes, regardless of how well their pancreas is still functioning.

Both medications have extensive clinical evidence supporting their effectiveness in controlling blood sugar levels and reducing the risk of diabetes-related complications. They also offer benefits beyond blood sugar control, including cardiovascular protection.

What We Know About Cinnamon and Blood Sugar

People sometimes ask about cinnamon in relation to blood sugar management, which is why the question of interactions with diabetes medications comes up. However, there’s no conclusive scientific evidence demonstrating that cinnamon has significant effects on blood sugar levels.

There are different varieties of cinnamon that are relevant to these discussions. Ceylon cinnamon and the more common Cassia cinnamon found in grocery stores contain different compounds. Ceylon cinnamon is often considered the “true” cinnamon and contains lower levels of coumarin, a compound that can be harmful in large amounts. Cassia cinnamon, which is more readily available and less expensive, contains higher levels of coumarin.

High coumarin intake can pose health risks, particularly to liver function. Excessive consumption of coumarin-rich Cassia cinnamon may lead to liver damage in sensitive individuals. There is an established tolerable daily intake of coumarin at 0.1 mg per kilogram of body weight, which means that just one teaspoon of Cassia cinnamon could exceed safe limits for some people when consumed regularly.

Any potential effects of cinnamon on blood sugar would be minimal compared to prescription diabetes medications, such as Ozempic or Jardiance. While the idea of a natural supplement helping to control blood sugar levels might be appealing, it’s essential to maintain realistic expectations about what cinnamon can achieve in terms of diabetes management.

cinnamon is in a bowl on the table

The Answer: No Known Interactions, But Here’s What You Should Know

There are no known drug interactions between cinnamon and either Ozempic or Jardiance. However, cinnamon may slightly decrease insulin sensitivity, which could potentially increase the risk of low blood sugar when combined with these medications. This effect means that while cinnamon supplements or consuming cinnamon in normal dietary amounts is not expected to interfere with how these medications work in your body, you should monitor your blood sugar more carefully if you use cinnamon regularly alongside your diabetes treatment.

There are no known drug interactions between cinnamon and either Ozempic or Jardiance. Therefore,  taking cinnamon supplements or consuming cinnamon in normal dietary amounts is not expected to interfere with how these medications work in your body.

Cinnamon is not listed as having interactions with any medications. Clinical studies of Ozempic and Jardiance have not reported problems when patients consumed cinnamon during the research trials.

However, the absence of documented interactions doesn’t automatically mean that combining cinnamon with these medications is beneficial or recommended.

The distinction between interaction and effect is important here. An interaction would mean that cinnamon changes how your medication works or that your medication changes how cinnamon affects your body. The current evidence suggests this type of interaction does not occur.

In practical terms, this means that using cinnamon in cooking or even taking cinnamon supplements is unlikely to cause problems with your Ozempic or Jardiance treatment. Your medications should continue to work as expected, and cinnamon supplements may even slightly improve insulin sensitivity, which could provide additional benefits for blood sugar management. However, you shouldn’t experience any adverse effects from the combination.

Focus on Proven Diabetes Treatment

The most important aspect of managing your diabetes remains consistent use of your prescribed medications. Ozempic and Jardiance have undergone extensive clinical testing to prove their safety and effectiveness for blood sugar control, with thousands of patients studied over many years.

These medications offer benefits that extend beyond blood sugar management. Ozempic has been shown to reduce the risk of cardiovascular events like heart attacks and strokes, while Jardiance provides additional protection for your heart and kidneys. These proven benefits make them valuable tools in comprehensive diabetes care that go far beyond what any supplement can offer.

While exploring complementary approaches like dietary supplements is understandable, the foundation of effective diabetes management rests on evidence-based treatments. Working closely with your healthcare provider to optimize your medication regimen, monitor your blood sugar levels, and make appropriate lifestyle adjustments will have the greatest impact on your long-term health outcomes.

Your diabetes medications work best when taken consistently and as prescribed. Missing doses or making changes without medical supervision can affect your blood sugar control and potentially lead to complications. The effectiveness of these medications depends on maintaining steady levels in your system, which requires adherence to your prescribed schedule.

If you’re interested in complementary approaches to diabetes management, focus on proven lifestyle interventions like regular physical activity, a balanced diet, stress management, and adequate sleep. These approaches work synergistically with your medications to improve your overall diabetes control and general health.

Fitness and healthy food promoting active lifestyle with dumbbells and fresh produce

Let The RX Advocates Help You Afford Your Diabetes Medications

Understanding that cinnamon doesn’t interact with your diabetes medications is important, but ensuring you can consistently afford your prescribed treatments is equally crucial. The cost of medications like Ozempic and Jardiance can be a significant financial burden, making it difficult to maintain consistent treatment.

The RX Advocates helps people access the medications they need through our patient assistance program. We work with pharmaceutical companies to help eligible individuals receive their prescriptions at reduced costs or sometimes free of charge. You shouldn’t have to choose between managing your diabetes effectively and financial stability.

If you’re struggling to afford your diabetes medications, we’re here to help. Contact The RX Advocates today at 844-559-8332 to see if you qualify for assistance and maintain access to the treatments that keep your diabetes well-managed.

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