Authored by Chris Schumacher / Medically Reviewed by Dr. Conor Sheehy, PharmD, BCPS
Last Updated: July 2025
Calquence (acalabrutinib) is a breakthrough medication used to treat certain types of blood cancer, including mantle cell lymphoma (MCL), small lymphocytic lymphoma (SLL), and chronic lymphocytic leukemia (CLL). As a targeted therapy, it works by blocking specific enzymes that help cancer cells grow and survive, offering hope for patients managing these conditions. While Calquence has revolutionized the treatment of certain cancers, its high price tag can be a significant concern for those who need it.
Good news! There are ways to make Calquence more affordable. While manufacturer coupons, copay cards, and discount programs may offer some short-term relief, they often come with restrictions. If you’re looking for a more reliable way to save, patient assistance programs can significantly lower the cost of Calquence. That’s where The Rx Advocates comes in, helping patients access these programs and keep their medication costs under control.
Calquence Cost
$80.00/month
Calquence Price
$16,908/month
* Source: GoodRx.com
Save on Calquence With The Rx Advocates
The Rx Advocates are well-versed in helping patients access over 800 FDA-approved medications, including Calquence, through trusted patient assistance programs. We work with over 100 pharmaceutical companies to secure meaningful savings for those who qualify.
Our pricing is simple and affordable:
- 1 Medication (Calquence only) – $80 per month
- 2 Medications (Calquence + 1 other) – $90 per month
- 3 Medications (Calquence + 2 others) – $100 per month
- 4+ Medications – $110 per month
With a one-time enrollment fee of $35 and no surprise fees, we handle all the heavy lifting, from application submission to follow-ups, so you can focus on your treatment without unnecessary stress.
Why Relying on a Calquence Coupon May Not Be Enough
Coupons and copay cards can seem like a quick fix for high prescription costs, but they are not always the best long-term solution. Here’s why:
- Limited Use: Many manufacturer coupons can only be used for a short time or are limited to new prescriptions.
- Insurance Challenges: Some insurance plans do not apply coupon savings toward deductibles or out-of-pocket limits, leaving patients with high expenses.
- Income Restrictions: Some discounts are only available to those who meet specific financial criteria, making it harder for many people to qualify.
- Temporary Savings: Coupons and discount cards eventually expire, meaning patients could be left with the full cost of the medication at any time.
For those who require Calquence as an ongoing treatment, patient assistance programs offer a more dependable way to save.
How The Rx Advocates Makes Calquence More Affordable
Rather than relying on short-term discounts, The Rx Advocates helps patients enroll in patient assistance programs offered by pharmaceutical companies. These programs can provide Calquence at a significantly reduced cost, helping patients afford their treatment without worrying about price fluctuations.
Our team handles the entire process, from checking eligibility and gathering paperwork to submitting applications and managing renewals. We take care of the details so patients can focus on their health instead of navigating complicated enrollment processes.
How much will it cost with The Rx Advocates?
If approved, by the Calquence Patient Assistance Program, you’ll be charged a fixed monthly service fee. This fee varies depending on the number of medications you qualify for. For example:
$80 / Month
$90 / Month
$100 / Month
$110 / Month
Who Qualifies for a Calquence Patient Assistance Program?
Eligibility requirements vary by program, but most follow similar financial guidelines. Patients typically qualify if they:
- Earn an annual income of $40,000 or less for an individual.
- Have a total household income of $100,000 or less.
- Do not have adequate prescription coverage for Calquence.
Because every case is different, The Rx Advocates assesses each patient’s situation to determine eligibility. If approved, we take care of the enrollment process to help make Calquence more affordable.
Can Other Medications Be Considered Instead of Calquence?
Data shows that a staggering 81 percent of patients who used Calquence achieved a response. There’s no denying that it is an effective targeted therapy, but it may not be the right fit for everyone. Some patients may experience side effects, have contraindications, or need a different treatment approach based on their medical history. If Calquence is not an option, a doctor may recommend an alternative medication.
If cost is a concern for Calquence, The Rx Advocates can help find financial assistance options. Always consult with a healthcare provider before switching treatments.
Why Patient Assistance Programs Are the Right Choice
Managing a serious condition like leukemia or lymphoma requires consistency in treatment. While coupons and discount cards can offer temporary savings, they often come with limitations that make them unreliable over time. If a coupon runs out, is rejected at the pharmacy, or no longer applies, patients may suddenly face high out-of-pocket costs.
Patient assistance programs provide a more stable solution by offering ongoing savings. The Rx Advocates simplifies the process by handling paperwork, renewals, and communication with the program, helping patients keep their costs manageable.
Calquence Coupon, Discounts, & Patient Assistance FAQ
No, these programs are designed for brand-name drugs like Calquence.
If an application is denied for all medications The Rx Advocates is assisting with, any monthly service fees paid will be refunded. However, the one-time $35 enrollment fee is non-refundable.
Most patients receive their first shipment within four to six weeks after enrolling.
Yes, some patient assistance programs accept patients with insurance, depending on their coverage and financial situation.
How to Apply for a Calquence Patient Assistance Program
Applying for a patient assistance program can be a complex process that involves submitting financial documents, insurance details, and a valid prescription, which can be overwhelming. With The Rx Advocates, we handle everything, including renewals, so you don’t have to deal with the hassle.
If the cost of Calquence is putting stress on your budget, The Rx Advocates is here to help. We determine eligibility, manage the paperwork, and provide ongoing support to keep medication costs as low as possible.
To learn more about how we can help, call 844-559-8332 or visit our website today!